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Objective To evaluate the prevalence of depression and quality of life and their correlation in non-dialysis patients with chronic renal failure and analyze the factors affecting the occurrence of depression in these patients. Methods This study was conducted among 356 non-dialysis patients with chronic renal failure (including both inpatients and outpatients) from 4 general hospitals in Chongqing during the period from May, 2017 to March, 2018. Beck Depression Inventory-Ⅱ (BDI-Ⅱ) was used to assess the patient's depression, and the quality of life the patients was assessed using Quality of Life Instrument for Chronic Disease-Chronic Renal Failure (QLICD-CRF2.0). Results The incidence of depression was 45.22% in the 356 patients with chronic renal failure without dialysis. The patients with depression had significantly lower quality of life scores (including the physiological function, psychological function, social function and total scores), but had significantly higher scores in the specific modules of response symptoms than those without depression (P < 0.05). Binary logistic regression analysis of depression and quality of life showed that occupation (OR=1.753, 95%CI: 1.352-2.273), hospitalization frequency (OR=1.221, 95%CI: 1.007-1.480), specific modules (OR=1.034, 95%CI: 1.011-1.058), psychological function (OR=0.922, 95%CI: 0.902-0.942), education level (OR=0.597, 95%CI: 0.394-0.906), and annual income of the family (OR=0.514, 95%CI: 0.346-0.765) were all independent risk factors for the occurrence of depression in these patients. Conclusion The incidence of depression is high in non-dialysis patients with chronic renal failure. The patients with depression have lower quality of life scores than those without depression. Occupation, hospitalization frequency, specific modules, psychological function, education level and annual income of the family may affect the quality of life among the non-dialysis patients. |
