Autor: |
EFSA Panel on Plant Protection Products and their Residues (EFSA PPR Panel), Antonio F Hernandez‐Jerez, Paulien Adriaanse, Annette Aldrich, Philippe Berny, Tamara Coja, Sabine Duquesne, Anne Louise Gimsing, Marina Marinovich, Maurice Millet, Olavi Pelkonen, Silvia Pieper, Aaldrik Tiktak, Christopher J Topping, Ioanna Tzoulaki, Anneli Widenfalk, Gerrit Wolterink, Diane Benford, Gabriele Aquilina, Margherita Bignami, Claudia Bolognesi, Riccardo Crebelli, Rainer Guertler, Francesca Marcon, Elsa Nielsen, Josef Rudolf Schlatter, Christiane Vleminckx, Daniela Maurici, Juan Manuel Parra Morte |
Jazyk: |
angličtina |
Rok vydání: |
2020 |
Předmět: |
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Zdroj: |
EFSA Journal, Vol 18, Iss 3, Pp n/a-n/a (2020) |
Druh dokumentu: |
article |
ISSN: |
1831-4732 |
DOI: |
10.2903/j.efsa.2020.6053 |
Popis: |
Abstract The Panel received a mandate from the European Commission to assess the genotoxic potential of triazine amine based on available information submitted by the applicants. Available information includes experimental genotoxicity data on triazine amine, Quantitative Structure–Activity Relationship (QSAR) analysis and read across with structurally similar compounds. Based on the overall weight of evidence, the Panel, in agreement with the cross‐cutting Working Group Genotoxicity, concluded that there is no concern for the potential of triazine amine to induce gene mutations and clastogenicity; however, the potential to induce aneugenicity was not adequately investigated. For a conclusion, an in vitro micronucleus assay performed with triazine amine would be needed. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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