Localization and potential role of prostate microbiota

Autor: Koichi Okada, Kentaro Takezawa, Go Tsujimura, Takahiro Imanaka, Sohei Kuribayashi, Norichika Ueda, Koji Hatano, Shinichiro Fukuhara, Hiroshi Kiuchi, Kazutoshi Fujita, Daisuke Motooka, Shota Nakamura, Yoshihisa Koyama, Shoichi Shimada, Norio Nonomura
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Druh dokumentu: article
ISSN: 2235-2988
DOI: 10.3389/fcimb.2022.1048319
Popis: IntroductionWe aimed to clarify the presence and localization of the prostate microbiota and examine its association with benign prostate enlargement (BPE).MethodsThe microbiota of prostate tissues and catheterized urine from 15 patients were analyzed by 16S metagenomic analysis and compared to show that the prostate microbiota was not a contaminant of the urinary microbiota. Fluorescence in situ hybridization (FISH) and in situ hybridization (ISH) using the specific probe for eubacteria was performed on prostate tissue to show the localization of bacteria in the prostate. The BPE group was defined as prostate volume ≥30 mL, and the non-BPE group as prostate volume
Databáze: Directory of Open Access Journals