Colorectal cancer in the course of familial adenomatous polyposis: natural history and treatment methods

Autor:	Agata Gronowska, Stanisław Głuszek, Jacek Bicki, Jarosław Matykiewicz
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	colorectal cancer familial adenomatous polyposis familial polyposis coli apc gene mutation Medicine
Zdroj:	Studia Medyczne, Vol 36, Iss 4, Pp 303-309 (2020)
Druh dokumentu:	article
ISSN:	1899-1874 2300-6722
DOI:	10.5114/ms.2020.102325
Popis:	Familial adenomatous polyposis (FAP) is a group of diseases, mostly caused by an APC suppressor gene mutation inherited in an autosomal dominant pattern. It results in numerous adenomas formed in the epithelium of the large intestine leading to colorectal cancer in 100% of cases, with the mean age of 39, and a high risk of other fatal neoplasms. There is no causative treatment possible. Total colectomy performed at the right time is the only way to prevent the individual from developing colorectal cancer. The aim of this study was to present the diagnostic performance and treatment methods of FAP. Fast diagnosis and strict surveillance of patients and their families are the most important for effective treatment.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/ea3b51aa4d174fa5865a233ffcffd115 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF