Letter the editor: serious methodological concerns about a recently published meta-analysis on oxygen therapy

Autor: Thomas Lass Klitgaard, Olav Lilleholt Schjørring, Frederik Mølgaard Nielsen, Christian Sylvest Meyhoff, Marija Barbateskovic, Jørn Wetterslev, Anders Perner, Bodil Steen Rasmussen
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Intensive Care, Vol 9, Iss 1, Pp 1-5 (2021)
Druh dokumentu: article
ISSN: 2052-0492
DOI: 10.1186/s40560-021-00573-5
Popis: Abstract In a recent paper, Chen et al. report the findings of a systematic review with meta-analysis concerning conservative versus conventional oxygen therapy for critically ill patients. We wish to commend the authors for their interest in the matter. However, the authors appear to misquote findings, fail to report results for all specified analyses, do not identify all relevant trials, have post hoc changed the eligibility criteria, and have seemingly switched directions of effects in analyses of secondary outcomes. These issues have led to incorrect conclusions concerning the effects of targeted oxygen therapy in critically ill patients.
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