Autonomous precision resuscitation during ground and air transport of an animal hemorrhagic shock model

Autor:	Michael R. Pinsky, Hernando Gomez, Francis X. Guyette, Leonard Weiss, Artur Dubrawski, Jim Leonard, Robert MacLachlan, Lisa Gordon, Theodore Lagattuta, David Salcido, Ronald Poropatich
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Animal model Closed-loop Hemorrhagic shock Resuscitation Transport Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
Zdroj:	Intensive Care Medicine Experimental, Vol 12, Iss 1, Pp 1-12 (2024)
Druh dokumentu:	article
ISSN:	2197-425X
DOI:	10.1186/s40635-024-00628-5
Popis:	Abstract We tested the ability of a physiologically driven minimally invasive closed-loop algorithm, called Resuscitation based on Functional Hemodynamic Monitoring (ReFit), to stabilize for up to 3 h a porcine model of noncompressible hemorrhage induced by severe liver injury and do so during both ground and air transport. Twelve animals were resuscitated using ReFit to drive fluid and vasopressor infusion to a mean arterial pressure (MAP) > 60 mmHg and heart rate
Databáze:	Directory of Open Access Journals
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