| Autor: |
Ana Luisa Riul Sório, Paula Katherine Vargas‐Sanchez, Roger Rodrigo Fernandes, Dimitrius Leonardo Pitol, Luiz Gustavo de Sousa, Adriano Luiz Balthazar Bianchini, Geraldo Batista de Melo, Selma Siessere, Karina Fittipaldi Bombonato‐Prado |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Animal Models and Experimental Medicine, Vol 2, Iss 3, Pp 169-177 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2576-2095 |
| DOI: |
10.1002/ame2.12073 |
| Popis: |
Abstract Background The purpose of the study was to analyze the effect of cell therapy on the repair process in calvaria defects in rats subjected to irradiation. Methods Bone marrow mesenchymal cells were characterized for osteoblastic phenotype. Calvariae of male Wistar rats were irradiated (20 Gy) and, after 4 weeks, osteoblastic cells were placed in surgically created defects in irradiated (IRC) and control animals (CC), paired with untreated irradiated (IR) and control (C) animals. After 30 days, histological and microtomographic evaluation was performed to establish significant (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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