New Lignans from the Leaves and Stems of Kadsura philippinensis

Autor: Chang-Hung Chou, Yao-Haur Kuo, Michael Y. Chiang, I-Wen Lo, Chia-Ching Liaw, Yuan-Bin Cheng, Yu-Chi Lin, Ya-Ching Shen
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Molecules, Vol 18, Iss 6, Pp 6573-6583 (2013)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules18066573
Popis: Three novel C19 homolignans, taiwankadsurins D (1), E (2) and F (4), and two new C18 lignans kadsuphilins N (3) and O (5) were isolated from the aerial parts of Taiwanese medicinal plant Kadsura philippinensis. The structures of compounds 1–5 were determined by spectroscopic analyses, especially 2D NMR techniques. The structure of compound 5 was further confirmed by X-ray crystallographic analysis. Compounds 1 and 2 have a 3,4-{1'-[(Z)-2''-methoxy-2''-oxoethylidene]}-pentano(2,3-dihydrobenzo[b]furano)-3-(2'''-methoxycarbonyl-2'''-hydroxy-2''',3'-epoxide) skeleton.
Databáze: Directory of Open Access Journals