The effect of continuous positive airway pressure therapy on the prevalence of masked hypertension in obstructive sleep apnea patients

Autor: Milan Sova, Eliska Sovova, Milada Hobzova, Jana Zapletalova, Monika Kamasova, Vitezslav Kolek
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Biomedical Papers, Vol 159, Iss 2, Pp 277-282 (2015)
Druh dokumentu: article
ISSN: 1213-8118
1804-7521
DOI: 10.5507/bp.2014.063
Popis: Background and Aim. Obstructive sleep apnea (OSA) is a common cause of secondary arterial hypertension. Masked hypertension (MH) is defined as normal office blood pressure and abnormal results in 24 h ambulatory blood pressure monitoring (ABPM). The aim of this study was to evaluate the effect of CPAP therapy on the prevalence of MH in patients with OSA. Methods: 43 patients (40 men) were included, average age 54.2±10.5 years. All underwent sleep study (PG or PSG) with a diagnosis of OSA indicated for CPAP treatment, average apnea-hypopnea index (AHI) 60.6±23.6. Patients were treated with CPAP for one year. Ambulatory blood pressure monitoring was performed before and after one year of treatment. Results: Masked hypertension was initially present in 25 (58.1%) and in 26 (60.5%) patients after one year of CPAP therapy. However, there was a statistically significant improvement in BP for all evaluated intervals of ABPM with the exception of systolic pressure during the daytime. Conclusions: Masked hypertension was very prevalent in these patients with OSA. The CPAP treatment for one year however had no affect on prevalence of masked hypertension although there was a positive effect of CPAP treatment on blood pressure for all assessed intervals of ABPM with the exception of systolic BP during daytime.
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