Advanced Radiotherapy Techniques for Mediastinal Lymphomas: Results from an Italian Survey

Autor: Anna Di Russo, Gabriele Simontacchi, Andrea Emanuele Guerini, Andrea Riccardo Filippi, Mario Levis, Patrizia Ciammella, Vitaliana De Sanctis, Stefano Vagge, Sofia Meregalli, Giuseppina De Marco, Biancaluisa Lanfranchi, Luigi Spiazzi, Michela Buglione
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Hemato, Vol 2, Iss 3, Pp 496-504 (2021)
Druh dokumentu: article
ISSN: 2673-6357
DOI: 10.3390/hemato2030031
Popis: Background: Multiple methods have been implemented to limit the impact of radiotherapy on patients affected by mediastinal lymphoma, including breathing control techniques, image-guided radiotherapy (IGRT) and intensity-modulated radiotherapy (IMRT), although the actual diffusion of such techniques is unclear. No surveys have been published to date evaluating the techniques adopted at different centers. Methods: A survey with a dedicated questionnaire was submitted to 195 Italian radiotherapy centers, assessing items regarding the characteristics of the center and clinical practice in the treatment of mediastinal lymphomas. Results: A total of 43 centers (22%) responded, the majority of which were university hospitals (37.2%) or cancer care centers (27.9%). In 95.4% of the centers, IMRT was used in the clinical practice, and the most frequently employed techniques were VMAT (48.8% of centers) and non-rotational IMRT (31.7%). Comparison of multiple plans was performed by 66.7% of the responding centers. Dose constraints for organs at risk were consistently prescribed. IGRT techniques were adopted by 93% of the centers, while breathing control or gating techniques were routinely used by only 25.6% of the centers. A necessity to standardize OAR constraints and define guidelines was perceived by almost all participants. Conclusions: Modern radiotherapy techniques are widely used in the Italian centers, although with heterogeneous characteristics.
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