Transcranial electrical stimulation motor-evoked potentials in a spinal cord ischaemia rabbit model

Autor: Yucheng Lu, Baotao Lv, Qimin Song
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Chinese Neurosurgical Journal, Vol 5, Iss 1, Pp 1-8 (2019)
Druh dokumentu: article
ISSN: 2057-4967
DOI: 10.1186/s41016-019-0174-7
Popis: Abstract Background Spinal cord ischaemia animal models were established by selective ligation of the lumbar artery in a craniocaudal direction between the renal artery and the aortic bifurcation. Transcranial electrical stimulation motor-evoked potentials were measured to enable their use in future studies on spinal cord ischaemia protection. Methods Thirty-three New Zealand rabbits were randomly divided into 6 groups. Transcranial electrical stimulation motor-evoked potentials were recorded before vascular ligation, 30 min after vascular ligation, and 2 days after vascular ligation. Motor functions were assessed after surgery and 2 days after vascular ligation. The specimens were taken 2 days after ligation for histopathologic observation. Results With increased numbers of ligations, a transient extension of the latency became clear, but there were no significant differences in the statistical analysis. Analysis of variance after ligation at the same time in each group and t tests before and after ligation (P > 0.05) were not significant. One or 2 ligations did not cause spinal cord ischaemic damage. There were no significant differences before and after ligation for the amplitude (P > 0.05). With increased numbers of ligations, the amplitude before and after ligation was gradually reduced in the 3–5 ligation groups (P
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