Key Features of Gamma-Delta T-Cell Subsets in Human Diseases and Their Immunotherapeutic Implications

Autor:	Myriam Lawand, Julie Déchanet-Merville, Marie-Caroline Dieu-Nosjean
Jazyk:	angličtina
Rok vydání:	2017
Předmět:	human gamma-delta T cell cytotoxicity cytokine NK receptor antigen presentation cancer Immunologic diseases. Allergy RC581-607
Zdroj:	Frontiers in Immunology, Vol 8 (2017)
Druh dokumentu:	article
ISSN:	1664-3224
DOI:	10.3389/fimmu.2017.00761
Popis:	The unique features of gamma-delta (γδ) T cells, related to their antigen recognition capacity, their tissue tropism, and their cytotoxic function, make these cells ideal candidates that could be targeted to induce durable immunity in the context of different pathologies. In this review, we focus on the main characteristics of human γδ T-cell subsets in diseases and the key mechanisms that could be explored to target these cells.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/3775da7091df4085b1d306ec1cabc90c Zobrazit plný text záznamu View record in DOAJ