Defining the correlates of lymphopenia and independent predictors of poor clinical outcome in adults hospitalized with COVID-19 in Australia

Autor:	Priyanka Hastak, Deborah Cromer, James Malycha, Christopher R. Andersen, Eamon Raith, Miles P. Davenport, Mark Plummer, Sarah C. Sasson
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Lymphopenia COVID-19 Mortality Hospital length of stay Intensive care unit (ICU) Medicine Science
Zdroj:	Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Druh dokumentu:	article
ISSN:	2045-2322
DOI:	10.1038/s41598-024-61729-5
Popis:	Abstract Lymphopenia is a common feature of acute COVID-19 and is associated with increased disease severity and 30-day mortality. Here we aim to define the demographic and clinical characteristics that correlate with lymphopenia in COVID-19 and determine if lymphopenia is an independent predictor of poor clinical outcome. We analysed the ENTER-COVID (Epidemiology of hospitalized in-patient admissions following planned introduction of Epidemic SARS-CoV-2 to highly vaccinated COVID-19 naïve population) dataset of adults (N = 811) admitted for COVID-19 treatment in South Australia in a retrospective registry study, categorizing them as (a) lymphopenic (lymphocyte count
Databáze:	Directory of Open Access Journals
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