Paraneoplastic cerebellar degeneration in a patient with ovarian cancer

Autor: Hung-Ju Chien, Chuo-Yu Lee, Lu-An Chen, Chao-Chih Wu, Chih-Long Chang
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Taiwanese Journal of Obstetrics & Gynecology, Vol 54, Iss 3, Pp 313-315 (2015)
Druh dokumentu: article
ISSN: 1028-4559
DOI: 10.1016/j.tjog.2014.03.012
Popis: Objective: Herein, we report a case of ovarian serous carcinoma with paraneoplastic cerebellar degeneration. Case report: A 44-year-old female presented to our hospital with dizziness, slurred speech, and ataxic gait. Brain magnetic resonance imaging was normal. A lumbar puncture revealed a normal cell count in the cerebrospinal fluid, but slightly elevated protein. Her serum cancer antigen -125 level was high (2126.4 U/mL), and abdominal computed tomography disclosed a pelvic mass measuring 11 cm in diameter. Exploratory laparotomy was then performed, and a frozen section of the tumor revealed serous carcinoma. Conclusion: According to the surgical findings and pathological report, The International Federation of Gynecology and Obstetrics (FIGO) Stage IIIC, Grade 3, serous-type ovarian cancer was diagnosed. Due to the abovementioned symptoms and signs, we performed a serial test to document the presence of anti-Yo antibody in this patient.
Databáze: Directory of Open Access Journals