VKORC1 gene -1639 G/A and 1173 C/Т polymorphisms in Nenets autonomous district indigenous population
| Autor: | P. A. Lavrinov, N. I. Belova, N. A. Vorobyeva |
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| Jazyk: | ruština |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, Vol 21, Iss 2, Pp 33-36 (2014) |
| Druh dokumentu: | article |
| ISSN: | 1607-4181 2541-8807 |
| DOI: | 10.24884/1607-4181-2014-21-2-33-36 |
| Popis: | According to the data obtained the VKORC1 gene polymorphism prevalence in the native population of the Nenets autonomous region differed significantly from that in the Arkhangelsk population. The homozygous form of 1173T allele prevailed in the nenets. This may be protective against thrombosis but it increases the risk of artery calcification and of indirect overdosing of anticoagulants. |
| Databáze: | Directory of Open Access Journals |
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