Estado actual de la resistencia de Helicobacter pylori a tetraciclina: revisión sistemática de la literatura
| Autor: | Marcela Mercado-Reyes, Jenny Avila-Coy, Alba Alicia Trespalacios-Rangel, Paola Ramírez-Bulla, William Otero-Regino |
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| Jazyk: | English<br />Spanish; Castilian |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Universitas Scientiarum, Vol 17, Iss 2, Pp 216-229 (2012) |
| Druh dokumentu: | article |
| ISSN: | 0122-7483 2027-1352 |
| Popis: | Current status of Helicobacter pylori resistance to tetracycline: a systematic review of the literature. Objective. To determinethe prevalence of Helicobacter pylori resistance to and the possible mutations that generate this worldwide resistance. Materials andmethods. A systematic search for literature was performed in the databases Medline, Science Direct (Elsevier), Ovid, PubMed, Lilacsand MedicLatina using relevant key words. Data extraction was independent and checklists were prepared to assess the methodologicalquality of the studies. Analysis of information was done with RevMan 5®. Results. We found Helicobacter pylori resistance prevalencerates of 1% for North America, 8% for Central and South America, 5% for Asia, and 2% for Europe. The mutation associated to thisresistance is in the 16S rDNA gene at nucleotide position 967TTC to AGA965 responsible of high resistance to tetracycline. Conclusions.Antibiotic resistance is one of the causes most associated to treatment failure in the eradication of Helicobacter pylori, as well as pooradherence to treatment and indiscriminate use of antibiotics. We also evidenced that the rate of tetracycline resistance is higher whenit is used in a second treatment scheme. The distribution of resistance is variable in different areas and it is important to know these resistances to avoid treatment failures. |
| Databáze: | Directory of Open Access Journals |
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