The importance of determining human placental lactogen in the third trimester of pregnancy

Autor: Durković Jasmina, Mandić Bojana
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: Journal of Medical Biochemistry, Vol 28, Iss 2, Pp 97-100 (2009)
Druh dokumentu: article
ISSN: 1452-8258
1452-8266
Popis: Human placental lactogen (HPL) is a hormone produced by the placenta with a role in the regulation of fetoplacental growth. In this paper, the results of HPL determination in the third trimester of pregnancy are presented with the aim of testing the sensitivity of this biochemical marker for detecting placental dysfunction, fetal vitality and risk of bad outcome. The tests were performed on 370 women with high-risk pregnancy, between the 20th and 36th week of pregnancy. HPL was determined by an ELISA method using Bioserv Diagnostics tests and the results were read by a STAT-FAX 303+ reader. When compared to normal pregnancy, a significant decrease in the level of HPL biomarker was identified in preeclampsia (p
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