Locational effects on oral microbiota among long-term care patients
| Autor: | Fa-Tzu Tsai, Ding-Han Wang, Cheng-Chieh Yang, Yu-Cheng Lin, Lin-Jack Huang, Wei-Yu Tsai, Chang-Wei Li, Wun-Eng Hsu, Hsi-Feng Tu, Ming-Lun Hsu |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Journal of Oral Microbiology, Vol 14, Iss 1 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2000-2297 20002297 |
| DOI: | 10.1080/20002297.2022.2033003 |
| Popis: | Background Dysbiosis of oral microbiota is the cause of many diseases related to oral and general health. However, few Asia-based studies have evaluated the role of oral microbiota in patients receiving long-term care. Thus, new indications are needed for early prevention and risk management based on information derived from the oral microbiota. Methods We used next-generation sequencing (NGS) to identify the oral bacterial composition and abundance in patients receiving long-term care: 20 from the outpatient department (OPD) and 20 home-care patients. Their microbial compositions, taxonomy, and alpha/beta diversity were characterized. Results Microbiota from the two groups showed different diversity and homogeneity, as well as distinct bacterial species. A more diverse and stable microbial population was observed among OPD patients. Our findings indicated that home-care patients had a higher risk of oral diseases due to the existence of dominant species and a less stable microbial community. Conclusion This work was the first in Taiwan to use NGS to investigate the oral microbiota of long-term care patients. Our study demonstrated the potential use of dominant bacterial species as biomarkers for the risk management of posttreatment complications. |
| Databáze: | Directory of Open Access Journals |
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