| Autor: |
Liqun Zhou, Kaiwei Yang, Xuesong Li, Yi Ding, Dawei Mu, Hanzhong Li, Yong Yan, Jinyi Li, Dongwen Wang, Wei Li, Yulong Cong, Jiangping Gao, Kewei Ma, Yajun Xiao, Sheng Zhang, Hongyi Jiang, Weilie Hu, Qiang Wei, Xunbo Jin, Zhichen Guan, Qingyong Liu, Danfeng Xu, Xin Gao, Yongguang Jiang, Weimin Gan, Guang Sun, Qing Wang, Yanhui Liu, Jianquan Hou, Liping Xie, Xishuang Song, Fengshuo Jin, Jiafu Feng, Ming Cai, Zhaozhao Liang, Jie Zhang, Dingwei Ye, Lin Qi, Lulin Ma, Jianzhong Shou, Yuping Dai, Jianyong Shao, Ye Tian, Shizhe Hong, Tao Xu, Chuize Kong, Zefeng Kang, Yuexin Liu, Xun Qu, Benkang Shi, Shaobin Zheng, Yi Lin, Shujie Xia, Dong Wei, Jianbo Wu, Weiling Fu, Zhiping Wang, Jianbo Liang |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Asian Journal of Urology, Vol 6, Iss 1, Pp 114-121 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2214-3882 |
| DOI: |
10.1016/j.ajur.2018.06.001 |
| Popis: |
Objective: To evaluate the diagnostic value of fluorescence in situ hybridization (FISH) in bladder cancer. Methods: We enrolled healthy volunteers and patients who were clinically suspected to have bladder cancer and conducted FISH tests and cytology examinations from August 2007 to December 2008. Receiver operating characteristic (ROC) curve analysis was performed and the area under curve (AUC) values were calculated for both the FISH and urine cytology tests. Results: A cohort of 988 healthy volunteers was enrolled to establish a reference range for the normal population. A total of 4807 patients with hematuria were prospectively, randomly enrolled for the simultaneous analysis of urine cytology, FISH testing, and a final diagnosis as determined by the pathologic findings of a biopsy or a surgically-excised specimen. Overall, the sensitivity of FISH in detecting transitional-cell carcinoma was 82.7%, while that of cytology was 33.4% (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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