Endocrine-Disrupting Chemicals Role in Drug Abuser: A Review Study

Autor: Idha Arfianti Wiraagni, Mustafa Ali Mohd, Rusdi Abdul Rashid, Didi Erwandi Bin Mohamad Haron
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: International Journal of Medical Toxicology and Forensic Medicine, Vol 10, Iss 4 (2020)
Druh dokumentu: article
ISSN: 2251-8762
2251-8770
DOI: 10.32598/ijmtfm.v10i4.26324
Popis: Endocrine-disrupting Chemicals (EDCs) are exogenous chemicals that influence many aspects of natural hormone actions. Bisphenol is used in the industry, for increasing the thickness and durability of materials in certain plastics and resins. Paraben is used as preservatives in many pharmaceuticals, cosmetics, and some food products. EDCs can increase estrogen levels inside the body, and estrogen itself can increase the monoamine effect (dopamine, serotonin), neuronal excitability, neuropeptide transmitter mechanism, and drug metabolism. In drug abusers, this effect can develop greater craving behavior, addiction, and relapse.
Databáze: Directory of Open Access Journals