Value of ultrasound fusion imaging in detecting vascular cerebral white matter pathology

Autor: Cornelia Brunner, Stephan Joachim Schreiber, Martin Bokemeyer, Gerhard Ransmayr, Walter Struhal, Elisabeth Daniela Olbert, Naela Alhani, Milan Rastislav Vosko
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: The Ultrasound Journal, Vol 14, Iss 1, Pp 1-8 (2022)
Druh dokumentu: article
ISSN: 2524-8987
DOI: 10.1186/s13089-022-00275-5
Popis: Abstract Background Transcranial sonography is beside magnetic resonance imaging (MRI) and computed tomography, a well-established imaging method for evaluation of brain parenchyma and already implicated in various neurological disorders as bed-side investigation possibility in clinical routine. The aim of this study was the qualitative assessment detecting vascular white matter hyperintensities (WMHs), with ultrasound fusion-imaging technique (UFI) and to find the optimal location for their visualization in accordance to the grade of WMHs and to possibly providing a standardized protocol for clinical use. Results 29 patients with WMHs of variable degree quantified according to Fazekas grading scale (n = 13 I; n = 9 II; n = 7 III) and 11 subjects with normal findings on MRI were identified for further analysis. Ultrasound images were analyzed to a standardized protocol and predefined anatomical landmarks. UFI could visualize the MRI-verified WMHs in 147 of 161 localizations (91%). The overall ultrasound detection rate of WMHs increased with higher degree of WMHs burden (I:85%, II:94%, III:97%). The highest sensitivity was achieved at the contralateral central part (CPc) (97%) of the lateral ventricle. The inter-rater analysis between 2 independent raters, who were blinded to the patient’s diagnosis and assessed only the B-mode ultrasound images, indicated an 86% agreement with an overall moderate strength of agreement (κ: 0.489, p
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