Decoding trends in mRNA vaccine research: A comprehensive bibliometric study

Autor: Chaobin Zhang, Yuhang Wang, Jianding Peng, Xiaotian Wen, Youwen Zhang, Kejun Li, Hanjian Du, Xiaofei Hu
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
Druh dokumentu: article
ISSN: 21645515
2164-554X
2164-5515
DOI: 10.1080/21645515.2024.2355037
Popis: Background: In recent years, infectious diseases like COVID-19 have had profound global socio-economic impacts. mRNA vaccines have gained prominence due to their rapid development, industrial adaptability, simplicity, and responsiveness to new variants. Notably, the 2023 Nobel Prize in Physiology or Medicine recognized significant contributions to mRNA vaccine research. Methods: Our study employed a comprehensive bibliometric analysis using the Web of Science Core Collection (WoSCC) database, encompassing 5,512 papers on mRNA vaccines from 2003 to 2023. We generated cooperation maps, co-citation analyses, and keyword clustering to evaluate the field’s developmental history and achievements. Results: The analysis yielded knowledge maps highlighting countries/institutions, influential authors, frequently published and highly cited journals, and seminal references. Ongoing research hotspots encompass immune responses, stability enhancement, applications in cancer prevention and treatment, and combating infectious diseases using mRNA technology. Conclusions: mRNA vaccines represent a transformative development in infectious disease prevention. This study provides insights into the field’s growth and identifies key research priorities, facilitating advancements in vaccine technology and addressing future challenges.
Databáze: Directory of Open Access Journals