Pre-exercise and acute movement-evoked pain trajectories during a 24-week outdoor walking program for knee osteoarthritis (WALK)

Autor: S.J.J. Drummen, D. Aitken, S. Balogun, K.L. Bennell, R.S. Hinman, M.L. Callisaya, P. Otahal, L. Blizzard, B. Antony, I.P. Munugoda, T. Winzenberg, G. Jones, L.E.J.M. Scheepers
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Osteoarthritis and Cartilage Open, Vol 6, Iss 3, Pp 100481- (2024)
Druh dokumentu: article
ISSN: 2665-9131
DOI: 10.1016/j.ocarto.2024.100481
Popis: Objectives: Exploring (1) pre-exercise and acute movement-evoked pain (AMEP) during an outdoor walking program in individuals with knee osteoarthritis (OA); and (2) comparing baseline physical performance and AMEP flares initiated by walking between participants with either a higher or lower attendance rate. Methods: Individuals with knee OA were prescribed a 24-week walking program, including one unsupervised walk and two supervised walk classes per week. Participants self-reported knee pain on a numerical rating scale (NRS; 0–10) before and after each supervised class. Mixed-effects models were used to investigate trajectories over time for pre-exercise pain and AMEP change (post-minus pre-exercise pain; positive value indicates flare-up). Baseline physical performance (6 tests) and AMEP flares were compared between participants with higher (attending ≥70% of supervised classes) and lower attendance rates. Results: Of 24 participants commencing the program, 7 (29%) withdrew. Over 24 weeks, pre-exercise pain improved by 1.20 NRS (95% CI -1.41 to −0.99), with estimated largest per class improvements during the first 8 weeks (−0.05 (−0.06 to −0.03) and plateauing around 20-weeks. The AMEP was estimated to improve by 0.19 NRS (95% CI -0.38 to −0.004) over 24-weeks, with improvements plateauing around 12-weeks. Participants with lower attendance (n ​= ​11) scored poorer on all physical performance tests and experienced a slight increase in AMEP during the first two weeks of the program. Conclusions: Participants improved in pre-exercise pain and AMEP in the first 20 and 12 weeks, respectively. Despite supervision, physical performance and AMEP flares may have contributed to lower attendance. Trial registration number: 12618001097235.
Databáze: Directory of Open Access Journals