vHDvDB 2.0: Database and Group Comparison Server for Hepatitis Delta Virus

Autor: Chi-Ching Lee, Yiu Chung Lau, You-Kai Liang, Yun-Hsuan Hsian, Chun-Hsiang Lin, Hsin-Ying Wu, Deborah Jing Yi Tan, Yuan-Ming Yeh, Mei Chao
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Viruses, Vol 16, Iss 8, p 1254 (2024)
Druh dokumentu: article
ISSN: 1999-4915
DOI: 10.3390/v16081254
Popis: The hepatitis delta virus (HDV) is a unique pathogen with significant global health implications, affecting individuals who are coinfected with the hepatitis B virus (HBV). HDV infection has profound clinical consequences, manifesting either as coinfection with HBV, resulting in acute hepatitis and potential liver failure, or as superinfection in chronic HBV cases, substantially increasing the risk of cirrhosis and hepatocellular carcinoma. Given the complex dynamics of HDV infection and the urgent need for advanced research tools, this article introduces vHDvDB 2.0, a comprehensive HDV full-length sequence database. This innovative platform integrates data preprocessing, secondary structure prediction, and epidemiological research tools. The primary goal of vHDvDB 2.0 is to consolidate HDV sequence data into a user-friendly repository, thereby facilitating access for researchers and enhancing the broader scientific understanding of HDV. The significance of this database lies in its potential to streamline HDV research by providing a centralized resource for analyzing viral sequences and exploring genotype-specific characteristics. It will also enable more in-depth research within the HDV sequence domains.
Databáze: Directory of Open Access Journals
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