| Autor: |
Grin Vladimir A., Rogaleva Eugenia V., Semenenko Marina P., Semenenko Ksenia A., Kuzminova Elena V. |
| Jazyk: |
English<br />French |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
E3S Web of Conferences, Vol 262, p 02004 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2267-1242 |
| DOI: |
10.1051/e3sconf/202126202004 |
| Popis: |
The article is devoted to the study of the assessment of selenium status in the pathogenesis of liver diseases and the effectiveness of the use of a selenium-containing drug. In the course of studies in animals with clinical signs and high rates of hepatopathies markers – transaminases, in 100% of cases a low level of selenium was revealed – 0.026 ±0.01 μg / ml, because of the increased consumption of this microelement on the background of increased free radical oxidation processes in the liver tissue. It was found that intramuscular administration of the drug selenolin at a dose of 20 mg / 100 kg four times with an interval of 15 days significantly improved the clinical status of the experimental animals; the effectiveness of therapy was 93.3%. Parenteral administration of selenolin favorably corrected the processes of lipid peroxidation and contributed to a significant (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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