Helicobacter pylori Seropositivity and Stool Antigen in Patients With Hyperemesis Gravidarum

Autor: R. Sinan Karadeniz, Ozlem Ozdegirmenci, M. Metin Altay, Ayse Solaroglu, Serdar Dilbaz, Nedret Hızel, Ali Haberal
Jazyk: angličtina
Rok vydání: 2006
Předmět:
Zdroj: Infectious Diseases in Obstetrics and Gynecology, Vol 2006 (2006)
Druh dokumentu: article
ISSN: 1064-7449
1098-0997
DOI: 10.1155/IDOG/2006/73073
Popis: The objective of this paper is to investigate whether Helicobacter pylori is an etiologic factor in hyperemesis gravidarum. Thirty one patients with hyperemesis gravidarum and twenty nine pregnant controls without hyperemesis gravidarum were included in this prospective study. All pregnant women were examined both for Helicobacter pylori serum immunoglobulin G antibodies (HpIgG Ab), showing chronic infection, and Helicobacter pylori stool antigens (HpSA), showing active gastrointestinal colonization. Chi-square and Student t tests were used accordingly for statistical analysis. Helicobacter pylori seropositivity was 67.7% in the patients with hyperemesis gravidarum and 79.3% in the control group (χ2=1.02,P=.31). HpSA was detected in 22.6% of patients with hyperemesis gravidarum, whereas 6.9% of patients in the control group. The difference was not statistically significant (χ2=2.89,P=.08). In this study, no relation was found between Helicobacter pylori and hyperemesis gravidarum. The low social status of women in both groups could be one of the reasons for the high prevalence of Hp infection.
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