Effects of a 2‐year exercise training on neuromuscular system health in older individuals with low muscle function

Autor: Elena Monti, Sara Tagliaferri, Sandra Zampieri, Fabio Sarto, Giuseppe Sirago, Martino Vladimiro Franchi, Andrea Ticinesi, Yari Longobucco, Elisa Adorni, Fulvio Lauretani, Stephan Von Haehling, Emanuele Marzetti, Riccardo Calvani, Roberto Bernabei, Matteo Cesari, Marcello Maggio, Marco Vincenzo Narici
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 2, Pp 794-804 (2023)
Druh dokumentu: article
ISSN: 2190-6009
2190-5991
DOI: 10.1002/jcsm.13173
Popis: Abstract Background Ageing is accompanied by a progressive loss of skeletal muscle mass and strength, potentially determining the insurgence of sarcopenia. Evidence suggests that motoneuron and neuromuscular junction (NMJ) degeneration contribute to sarcopenia pathogenesis. Seeking for strategies able to slow down sarcopenia insurgence and progression, we investigated whether a 2‐year mixed‐model training involving aerobic, strength and balance exercises would be effective for improving or preserving motoneuronal health and NMJ stability, together with muscle mass, strength and functionality in an old, sarcopenic population. Methods Forty‐five sarcopenic elderly (34 females; 11 males) with low dual‐energy X‐ray absorptiometry (DXA) lean mass and Short Physical Performance Battery (SPPB) score
Databáze: Directory of Open Access Journals
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