| Autor: |
Wu Gang, Fu Zhihao, Xu Gangling, Wang Wenbo, Yu Chuanfei, Wang Lan, Wang Junzhi |
| Jazyk: |
čínština |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
生物医学转化, Vol 2, Iss 4, Pp 1-11 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2096-8965 |
| DOI: |
10.12287/j.issn.2096-8965.20210401 |
| Popis: |
Through referring to the literature and related databases, the research process of antibodyconjugated drugs was reviewed, and the key elements of ADC were summarized. Twelve ADCs have been approved worldwide, since the therapeutic ADC was marketed for the first time in 2000. There are two imported and one domestic ADCs approved to date in China. In this paper, the development of ADCs in recent years was summarized, and the key elements of ADCs such as antigenic site, linker, payload and conjugation mode were reviewed in order to provide comprehensive information of ADCs and promote their research and development in the future. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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