Recent Progress on the [3+2] Cycloaddition Route for the Synthesis of All-Carbon Quaternary Stereocentres

Autor: Ani Deepthi, Maneesh Mohan, Meenakshy C. Balachandran
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: SynOpen, Vol 06, Iss 04, Pp 270-285 (2022)
Druh dokumentu: article
ISSN: 2509-9396
32111061
DOI: 10.1055/a-1947-3351
Popis: Construction of all-carbon quaternary centres is an important task in organic synthesis. In spite of the challenges associated with Csp3–Csp3 bond construction in a sterically constrained environment, significant advances have been made in this area. Among the latter, both catalytic and noncatalytic [3+2] cycloaddition approaches have gained wide attention recently. This short review summarizes the [3+2] cycloaddition reactions reported during the period 2016–2022 for the synthesis of molecules possessing one or more all-carbon quaternary stereocentres.
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