Fibrin microthrombi in bladder urothelium after SARS-CoV-2 infection: Case report

Autor: Ly Hoang Roberts, Bernadette M.M. Zwaans, Kausar Jabbar, Sarah N. Bartolone, Priya Padmanabhan, Kenneth M. Peters
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Urology Case Reports, Vol 51, Iss , Pp 102575- (2023)
Druh dokumentu: article
ISSN: 2214-4420
DOI: 10.1016/j.eucr.2023.102575
Popis: A 45-year-old male with diabetes, hypertension and hyperlipidemia was referred to urology due to persistent symptoms of urinary frequency, urgency, nocturia, erectile dysfunction, and constant pain localized to the bladder, pelvis, and perineal area, 3–4 months after SARS-CoV-2 infection. A bladder biopsy showed urothelial mucosa and submucosa with hemorrhage and fibrin microthrombi in blood vessels. Hydrodistention of the bladder and pelvic floor physical therapy resolved symptoms, though bladder and pain symptoms returned upon reinfection with SARS-CoV-2. Urinalysis revealed elevated urinary interleukin-8, which may indicate localized bladder inflammation.
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