Successful corneal endothelium preservation in the management of epithelial downgrowth with 5-fluorouracil injections and membranectomy

Autor: Ka Wai Kam, Andre Ma, Joanna Ng, Paul Choi, Wilson Wai Kuen Yip, Alvin L. Young
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMC Ophthalmology, Vol 24, Iss 1, Pp 1-7 (2024)
Druh dokumentu: article
ISSN: 1471-2415
DOI: 10.1186/s12886-024-03719-9
Popis: Abstract A 74-year-old Chinese man underwent extracapsular cataract extraction in his right eye and developed a translucent iris membrane 4 months later. He was treated with two intracameral 5-FU injections and membranectomy at 2 weeks apart. At one year following the second membranectomy, the patient maintained a clear cornea without residual or recurrent membrane, an endothelial cell density of 1072 cell/mm2, a visual acuity of 20/50 and a normal intraocular pressure. Our technique of using dispersive and cohesive viscoelastics in protecting the corneal endothelium from intracameral 5-FU, helped preserve corneal endothelial cells and maintain corneal clarity at one year after surgery.
Databáze: Directory of Open Access Journals