ANTIHYPERTENSIVE EFFICACY AND SAFETY OF OLMESARTAN MEDOXOMIL AND RAMIPRIL IN ELDERLY PATIENTS WITH MILD TO MODERATE ESSENTIAL HYPERTENSION: THE ESPORT STUDY

Autor:	E. Malacco, S. Omboni, M. Volpe, A. Auteri, A. Zanchetti
Jazyk:	ruština
Rok vydání:	2012
Předmět:	ambulatory blood pressure monitoring elderly essential hypertension office blood pressure olmesartan ramipril Diseases of the circulatory (Cardiovascular) system RC666-701
Zdroj:	Российский кардиологический журнал, Vol 0, Iss 1, Pp 52-62 (2012)
Druh dokumentu:	article
ISSN:	1560-4071 2618-7620
Popis:	Objective. To compare the efficacy and safety of the angiotensin II antagonist olmesartan medoxomil (O) and the ACE inhibitor ramipril (R) in elderly patients with essential arterial hypertension. Methods. After a 2-week placebo wash-out 1102 treated or untreated elderly hypertensive patients aged 65–89 years (office sitting diastolic blood pressure, DBP, 90–109mmHg and/or office sitting systolic blood pressure, SBP, 140–179mmHg) were randomized double-blind to 12-week treatment with O 10mg or R 2.5mg oncedaily. After the first 2 and 6 weeks doses could be doubled in non-normalized [blood pressure (BP)
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/3169e15704ad4e1d90e9b0a038360163 Zobrazit plný text záznamu View record in DOAJ