An overview on fundamentals of immediate release drug delivery system

Autor: Yogita Bundela, Dilip Agrawal, Gaurav Bhaduka
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Applied Pharmaceutical Research, Vol 10, Iss 3, Pp 01-04 (2022)
Druh dokumentu: article
ISSN: 2348-0335
DOI: 10.18231/j.joapr.2022.10.3.1.4
Popis: Tablet is most popular among all dosage forms today because of its convenience, ease of administration, greater flexibility in dosage form design, ease of production, and low cost and non-invasive therapy. Formulation of tablets requires API along with excipients. Excipients include lubricants, diluents, binders, glidants, disintegrants, sweetening agents, flavoring agents, etc. Recent trends indicate that multi-particulate drug delivery systems are suitable for achieving extended-release oral formulation with a low risk of dose dumping, mixing flexibility to attain difference release patterns, and reproducible and short gastric residence time. Modern technology in immediate-release tablets, such as novel granulation techniques and electrostatic dry powder coating techniques, are prevalent nowadays. Recently, the immediate-release formulation has been similar to various sustained-release formulations that are currently readily attainable.
Databáze: Directory of Open Access Journals