Lower diastolic wall strain is associated with coronary revascularization in patients with stable angina

Autor: Jaehuk Choi, Min-Kyung Kang, Chaehoon Han, Sang Muk Hwang, Sung Gu Jung, Han-Kyul Kim, Kwang Jin Chun, Seonghoon Choi, Jung Rae Cho, Namho Lee
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: BMC Cardiovascular Disorders, Vol 17, Iss 1, Pp 1-8 (2017)
Druh dokumentu: article
ISSN: 1471-2261
DOI: 10.1186/s12872-017-0739-3
Popis: Abstract Background Left ventricular (LV) diastolic dysfunction occurs earlier in the ischemic cascade than LV systolic dysfunction and electrocardiographic changes. Diastolic wall strain (DWS) has been proposed as a marker of LV diastolic stiffness. Therefore, the objectives of this study were to define the relationship between DWS and coronary revascularization and to evaluate other echocardiographic parameters in patients with stable angina who were undergoing coronary angiography (CAG). Methods Four hundred forty patients [mean age: 61 ± 10; 249 (57%) men] undergoing CAG and with normal left ventricular systolic function without regional wall motion abnormalities were enrolled. Among them, 128 (29%) patients underwent revascularization (percutaneous intervention: 117, bypass surgery: 11). All patients underwent echocardiography before CAG and the DWS was defined using posterior wall thickness (PWT) measurements from standard echocardiographic images [DWS = PWT(systole)-PWT(diastole)/PWT(systole)]. Results Patients who underwent revascularization had a significantly lower DWS than those who did not (0.26 ± 0.08 vs. 0.38 ± 0.09, p
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