Synthesis of silver nanoparticles using aqueous extract of Dolichos lablab for reduction of 4-Nitrophenol, antimicrobial and anticancer activities

Autor: Mebrahtu Hagos Kahsay, Dharmasoth RamaDevi, Y. Pavan Kumar, B. Sathish Mohan, Aschalew Tadesse, Gangarao Battu, K. Basavaiah
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: OpenNano, Vol 3, Iss , Pp 28-37 (2018)
Druh dokumentu: article
ISSN: 2352-9520
DOI: 10.1016/j.onano.2018.04.001
Popis: In this paper, we report for the first time an eco-friendly method for the preparation of silver nanoparticles (Ag NPs) using an aqueous leaf extract of Dolichos lablab as reducing and capping agents using UV–vis, FT-IR, XRD, FE-SEM, EDX and TEM. The crystallinity, phase purity, size and morphology of Ag NPs were investigated by UV–vis, FT-IR and XRD. The spectroscopic and microscopic results revealed the formation of Ag NPs. The morphology of Ag NPs is found to be spherical with an average diameter of 9 nm. As prepared Ag NPs effectively reduced the 4-Nitrophenol to 4-Aminophenol in the presence of NaBH4. The Ag NPs showed potent antimicrobial activity against Escherichia coli and Bacillus subtilis. Ag NPs also exhibited anticancer activity against human liver cancer (Hep G2) cell line. Keywords: Anticancer, Antimicrobial, Dolichos lablab, Green synthesis, 4-Nitrophenol, Silver nanoparticles
Databáze: Directory of Open Access Journals