An analytic approximation of the feasible space of metabolic networks

Autor: Alfredo Braunstein, Anna Paola Muntoni, Andrea Pagnani
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/ncomms14915
Popis: Large-scale metabolic models of organisms from microbes to mammals can provide great insight into cellular function, but their analysis remains challenging. Here, the authors provide an approximate analytic method to estimate the feasible solution space for the flux vectors of metabolic networks, enabling more accurate analysis under a wide range of conditions of interest.
Databáze: Directory of Open Access Journals