Reference ranges of fetal heart function using a Modified Myocardial Performance Index: a prospective multicentre, cross-sectional study

Autor: Xiaoming Zhang, Wei Zhao, Yuqing Zhou, Hong Lu, Jingjing Wang, Wei Guo, Wenjun Zhang, Sheng Zhao, Na Zhang, Lan Yu, Lijuan Sun, Yuxin Jiang, QingQing Wu, Zhen Li, Xiaoting Su, Xinlin Chen, Jianmei Niu, Congxin Sun, Jijing Han, Lina Zhang, Zhenna Wang, Peiwen Chen, Tiantian Chen, Hua Hong, Lulu Zhou, Baoying Ye, Jiawei Tian
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: BMJ Open, Vol 11, Iss 7 (2021)
Druh dokumentu: article
ISSN: 2044-6055
DOI: 10.1136/bmjopen-2021-049640
Popis: Objectives The primary aim of this study was to establish the normal reference ranges of the fetal left ventricular (LV) Modified Myocardial Performance Index (Mod-MPI). A secondary aim was to evaluate the agreement between manual and automatic measurements for fetal Mod-MPI.Design A prospective, multicentre, cross-sectional study.Participants Normal singleton pregnancies.Methods The LV functions of normal singleton pregnancies were assessed in nine centres covering eight provinces in China using unified ultrasound protocols and settings and standardised measurements by pulsed Doppler at 20–24, 28–32 and 34–38 weeks of gestation. The isovolumetric relaxation time (IRT), isovolumetric contraction time, ejection time (ET) and Mod-MPI were measured both automatically and manually.Results This cross-sectional study included 2081 fetuses, and there was a linear correlation between gestational age (GA) and Mod-MPI (0.416+0.001×GA (weeks), p
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