Revisit the practice of lymph node biopsy in patients diagnosed as ductal carcinoma in situ before operation: a retrospective analysis of 682 cases and evaluation of the role of breast MRI

Autor: Hung-Wen Lai, Yi-Lin Chang, Shou-Tung Chen, Yu-Jun Chang, Wen-Pei Wu, Dar-Ren Chen, Shou-Jen Kuo, Chiung-Ying Liao, Hwa-Koon Wu
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: World Journal of Surgical Oncology, Vol 19, Iss 1, Pp 1-11 (2021)
Druh dokumentu: article
ISSN: 1477-7819
DOI: 10.1186/s12957-021-02336-w
Popis: Abstract Background The optimal axillary lymph node (ALN) management strategy in patients diagnosed with ductal carcinoma in situ (DCIS) preoperatively remains controversial. The value of breast magnetic resonance imaging (MRI) to predict ALN metastasis pre-operative DCIS patients was evaluated. Methods Patients with primary DCIS with or without pre-operative breast MRI evaluation and underwent breast surgery were recruited from single institution. The value of breast MRI for ALN evaluation, predictors of breast and ALN surgeries, upgrade from DCIS to invasive cancer, and ALN metastasis were analyzed. Results A total of 682 cases with pre-operative diagnosis of DCIS were enrolled in current study. The rate of upgrade to invasive cancer were found in 34.2% of specimen, and this upgrade rate is 23% for patients who received breast conserving surgery and 40.7% for mastectomy (p
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