Leser-Trélat sign presenting in a patient with ovarian cancer: a case report

Autor: Bölke Edwin, Gerber Peter Arne, Peiper Matthias, Knoefel Wolfram Trudo, Cohnen Mathias, Matuschek Christiane, Budach Wilfried, Engers Rainer, Gripp Stephan
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: Journal of Medical Case Reports, Vol 3, Iss 1, p 8583 (2009)
Druh dokumentu: article
ISSN: 1752-1947
DOI: 10.4076/1752-1947-3-8583
Popis: Abstract Introduction Seborrheic keratoses are very common findings in elderly patients. However, a sudden onset and dramatic increase in the number and size of these benign lesions deserves special attention, since this may represent the Leser Trélat sign, a rare paraneoplastic cutaneous syndrome. Case presentation A 92-year-old female presented to our clinic with multiple eruptive seborrheic keratoses, which had dramatically increased in size and number over the past two years. A diagnostic work-up revealed an ovarian carcinoma. Hence, cutaneous findings in our patient were consistent with the diagnosis of the Leser-Trélat sign. Conclusion The Leser-Trélat sign may coincide with the diagnosis of occult cancer or follow or precede it by months or years. Practitioners should take cases of eruptive seborrheic keratoses seriously and perform thorough patient examinations.
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