Risk Factors for Periprosthetic Joint Infection in Total Knee Arthroplasty
| Autor: | Qunn Jid Lee, Wai Ping Mak, Yiu Chung Wong |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Journal of Orthopaedic Surgery, Vol 23 (2015) |
| Druh dokumentu: | article |
| ISSN: | 2309-4990 23094990 |
| DOI: | 10.1177/230949901502300303 |
| Popis: | Purpose. To evaluate the incidence and risk factors of periprosthetic joint infection (PJI) in patients undergoing total knee arthroplasty (TKA) in a high-volume hospital. Methods. Records of 1133 primary TKAs were reviewed. Correlation between surgery volume and infection rate was determined. Risk factors for PJI were identified using case-control analysis of variables. TKAs performed between October 2012 and March 2013 without infection were used as controls. Results. Of 1133 TKAs, 8 (0.71%) PJI occurred. The organisms involved were Staphylococcus aureus (n=4), coagulase-negative staphylococci (n=2), Pseudomonas aeruginosa (n=1), and methicillin-resistant S aureus (n=1). In the 6-month period chosen as the control period, one (0.52%) out of 192 TKAs developed PJI. Hospital annual volume did not correlate with infection rate (p=0.766). Significant risk factors included young age, comorbidities such as diabetes, anaemia, thyroid disease, heart disease, lung disease, and long operating time. Six of the 8 patients with PJIs had at least one risk factor. However, the number of patients with infection was too small to have sufficient power. Conclusion. Comorbidities are a risk factor for PJI. Perioperative optimisation of comorbidities and the use of antibiotic-loaded cement in patients with severe comorbidities should be considered. |
| Databáze: | Directory of Open Access Journals |
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