The pattern of human papillomavirus infection and genotypes among Nigerian women from 1999 to 2019: a systematic review

Autor: Anthony Uchenna Emeribe, Idris Nasir Abdullahi, Maisie Henrietta Etukudo, Idongesit Kokoabasi Isong, Anthony Ogbonna Emeribe, Justin Onyebuchi Nwofe, Chikodi Modesta Umeozuru, Buhari Isa Shuaib, Odunayo Rahmat Oyetola Ajagbe, Amos Dangana, Bibiana Nonye Egenti, Peter Elisha Ghamba
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Annals of Medicine, Vol 53, Iss 1, Pp 945-960 (2021)
Druh dokumentu: article
ISSN: 07853890
1365-2060
0785-3890
DOI: 10.1080/07853890.2021.1938201
Popis: AbstractBackground There are no robust national prevalence of Human Papillomavirus (HPV) genotypes in Nigerian women despite the high burden of cervical cancer morbidity and mortality.The objective of study This study aims to determine the pooled prevalence and risk factors of genital HPV infection in Nigeria through a systemic review protocol.Methods Databases including PubMed, Scopus, Google Scholar and AJOL were searched between 10 April to 28 July 2020. HPV studies on Nigerian females and published from April 1999 to March 2019 were included. GRADE was used to assess the quality of evidence.Results The pooled prevalence of cervical HPV was 20.65% (95%CI: 19.7–21.7). Genotypes 31 (70.8%), 35 (69.9%) and 16 (52.9%) were the most predominant HPV in circulation. Of the six geopolitical zones in Nigeria, northeast had the highest pooled prevalence of HPV infection (48.1%), while the least was in the north-west (6.8%). After multivariate logistic regression, duration (years) of sexual exposure (OR = 3.24, 95%CI: 1.78–9.23]), history of other malignancies (OR = 1.93, 95%CI: 1.03–2.97]), history of sexually transmitted infection (OR = 2.45, 95% CI: 1.31–3.55]), coital frequency per week (OR = 5.11, 95%CI: 3.86–14.29), the status of circumcision of the sexual partner (OR = 2.71, 95%CI: 1.62–9.05), and marital status (OR = 1.72, 95%CI: 1.16–4.72), were significant risk factors of HPV infection (p
Databáze: Directory of Open Access Journals
Externí odkaz: