Autor: |
Houjun Pan, Meiling Deng, Bin Zhang, Tiantian Fang, Yuguo Liu |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
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Zdroj: |
Heliyon, Vol 9, Iss 3, Pp e14069- (2023) |
Druh dokumentu: |
article |
ISSN: |
2405-8440 |
DOI: |
10.1016/j.heliyon.2023.e14069 |
Popis: |
Dihydroartemisinin (DHA) is a derivative of artemisinin and is toxic to parasites. We used the Tetrahymena thermophila (T. thermophila) as a model to explore DHA toxicity. Results showed that low concentration of DHA (20 μmol/L) promoted cell proliferation, whereas high concentrations of DHA (40–1280 μmol/L) inhibited that. Appearance of nucleus was pycnosis by laser scanning confocal microscope. DHA significantly elevated activities of SOD and GSH-Px (P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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