HOMA-IR index in non diabetic patient, a reliable method for early diagnosis of liver steatosis

Autor: Behrang Motamed, Mahsa Kohansal Vajargah, Saeed Kalantari, Afshin Shafaghi
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Caspian Journal of Internal Medicine, Vol 13, Iss 3, Pp 519-526 (2022)
Druh dokumentu: article
ISSN: 2008-6164
2008-6172
Popis: Background: NAFLD is one of the most common liver diseases in the world. HOMA-IR as an indicator of insulin resistance is commonly used in clinical trials in NAFLD patients. The aim of this study was to evaluate the application of HOMA-IR index in the diagnosis of NAFLD. Methods: This study was performed on 54 patients with NAFLD and 54 non-NAFLD patients that referred to Razi Hospital in Rasht during 2019-2020. FibroScan was used to diagnose NAFLD in the patient group and ultrasound was used to rule it out in the control group. Metabolic and hepatic parameters were measured for each patient. Data were entered into SPSS 22 software and the necessary analyses were performed. Results: The mean age of the subjects in the study was 44.01±13.12 years and ranged from 18 to 75 years. 72.2% of people affected by NAFLD were men (p
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