Prefrontal projections to the thalamic nucleus reuniens mediate fear extinction

Autor: Karthik R. Ramanathan, Jingji Jin, Thomas F. Giustino, Martin R. Payne, Stephen Maren
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-018-06970-z
Popis: Previous work has shown that the thalamic nucleus reuniens (RE) is involved in memory and emotion. Here the authors report that the RE and its inputs from the medial prefrontal cortex are indispensable for the top-down inhibition of fear memories after extinction.
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