| Autor: |
Wei Gao, Zhi Guo, Shumiao Shu, Wenge Xing, Weihao Zhang, Xueling Yang |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Asian Journal of Surgery, Vol 41, Iss 6, Pp 530-536 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
1015-9584 |
| DOI: |
10.1016/j.asjsur.2018.02.006 |
| Popis: |
Summary: Background/Objective: A retrospective review is required to assess the application effect of percutaneous cryoablation on the stage IIIB/IV advanced non-small-cell lung cancer (NSCLC) after the failure of chemoradiotherapy. A total of twenty-two cases with stage IIIB/IV advanced NSCLC after failure of chemoradiotherapy were enrolled. Methods: Computed Tomography (CT) was used for the assessment of tumor response, and Functional Assessment of Cancer Therapy-General (FACT-G) was applied for the evaluation of quality of life. After the treatment of cryoablation, we performed a follow-up analysis. Results: The primary technique effectiveness of 100% was observed in the one month of follow-up. At three months, local tumor progression was shown in 4 of 31 lesions (13.6%). The one-year survival rate of 81.8% and progression-free rate of 27.8% were obtained. Six patients died 7, 9, 10, 12, 15 and 22 months after treatment, respectively. Decreased scores of total quality of life at one week after cryoablation (P = 0.006), but increased scores at one month after cryoablation (P = 0.024) were observed, compared with pre-cryoablation. Conclusion: Cryoablation contributes to the effective local tumor therapy for stage IIIB/IV advanced NSCLC after the failure of chemoradiotherapy. Keywords: Cryoablation, Lung cancer, Stage IIIB/IV |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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