Thyroid Dysfunction and Associated Risk Factors among Nepalese Diabetes Mellitus Patients
| Autor: | Saroj Khatiwada, Rajendra KC, Santosh Kumar Sah, Seraj Ahmed Khan, Rajendra Kumar Chaudhari, Nirmal Baral, Madhab Lamsal |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | International Journal of Endocrinology, Vol 2015 (2015) |
| Druh dokumentu: | article |
| ISSN: | 1687-8337 1687-8345 |
| DOI: | 10.1155/2015/570198 |
| Popis: | Objectives. To assess thyroid function and associated risk factors in Nepalese diabetes mellitus patients. Methods. A cross-sectional study was carried out among 419 diabetes mellitus patients at B. P. Koirala Institute of Health Sciences, Dharan, Nepal. Information on demographic and anthropometric variables and risk factors for thyroid dysfunction was collected. Blood samples were analysed to measure thyroid hormones, blood sugar, and lipid profile. Results. Prevalence rate of thyroid dysfunction was 36.03%, with subclinical hypothyroidism (26.5%) as the most common thyroid dysfunction. Thyroid dysfunction was much common in females (42.85%) compared to males (30.04%) p=0.008 and in type 1 diabetes (50%) compared to type 2 diabetes mellitus (35.41%) p=0.218. Diabetic patients with thyroid dysfunction had higher total cholesterol, HDL cholesterol, and LDL cholesterol in comparison to patients without thyroid dysfunction. Significant risk factors for thyroid dysfunction, specifically hypothyroidism (overt and subclinical), were smoking (relative risk of 2.56 with 95% CI (1.99–3.29, p |
| Databáze: | Directory of Open Access Journals |
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