| Autor: |
David Köhler, Tiago Granja, Julia Volz, Michael Koeppen, Harald F. Langer, Georg Hansmann, Ekaterina Legchenko, Tobias Geisler, Tamam Bakchoul, Claudia Eggstein, Helene A. Häberle, Bernhard Nieswandt, Peter Rosenberger |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-020-14958-x |
| Popis: |
Reperfusion injury following myocardial ischemia is aggravated by inflammation and platelet–neutrophil complex formation. Here the authors show that semaphorin 7A binds to platelet GPIb, enhancing platelet–neutrophil interaction and increasing post-ischemic myocardial tissue injury, and that blockage of semaphorin 7A is protective. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
