| Autor: |
Ana Carolina Lobor Cancelier, Nikhil V. Dhurandhar, Swetha Peddibhotla, Richard L. Atkinson, Helena C.G. Silva, Daisson J. Trevisol, Fabiana Schuelter-Trevisol |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Jornal de Pediatria, Vol 97, Iss 4, Pp 420-425 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
0021-7557 |
| DOI: |
10.1016/j.jped.2020.08.002 |
| Popis: |
Objective: This study aimed to investigate human adenovirus 36 (Adv36) as an associated factor for adiposity in children and adolescents aged 9–12 years. Methods: This was a case-control study comparing overweight (cases) and eutrophic (controls) children and adolescents aged 9–12 years based on their body mass index in relation to human adenovirus 36 serology. Human adenovirus 36-specific neutralizing antibodies were assessed using the serum neutralization assay, and a questionnaire regarding the subjects’ personal backgrounds, breastfeed history, age of starting daycare, and eating and exercise habits was also applied. Results: A total of 101 (51, eutrophic; 50, overweight) children were included in the study. The Adv36 seropositivity rate was of 15.8%, which increased the chance of being overweight by 3.17 times (p = 0.049). Enrollment in a full-time daycare center before the age of 24 months increased the chance of being overweight by 2.78 times (p = 0.027). Metabolic parameters (total cholesterol and blood glucose) were insignificantly different among children who were seropositive or seronegative for human adenovirus 36. Conclusion: This study concluded that excessive weight was positively associated with seropositivity for human adenovirus 36. Early enrollment in a full-time daycare was also an associated factor for obesity. Such data, confirmed in new studies, reinforces the role of human adenovirus 36 in the increase of childhood adiposity. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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