Prediction of Male Coronary Artery Bypass Grafting Outcomes Using Body Surface Area Weighted Left Ventricular End-diastolic Diameter: Multicenter Retrospective Cohort Study

Autor: Zhihui Zhu, Yuehuan Li, Fan Zhang, Stefanie Steiger, Cheng Guo, Nan Liu, Jiakai Lu, Guangpu Fan, Wenbo Wu, Mingying Wu, Huaibin Wang, Dong Xu, Yu Chen, Junming Zhu, Xu Meng, Xiaotong Hou, Hans-Joachim Anders, Jian Ye, Zhe Zheng, Chenyu Li, Haibo Zhang
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Interactive Journal of Medical Research, Vol 12, p e45898 (2023)
Druh dokumentu: article
ISSN: 1929-073X
DOI: 10.2196/45898
Popis: BackgroundThe presence of a high left ventricular end-diastolic diameter (LVEDD) has been linked to a less favorable outcome in patients undergoing coronary artery bypass grafting (CABG) procedures. However, by taking into consideration the reference of left ventricular size and volume measurements relative to the patient's body surface area (BSA), it has been suggested that the accuracy of the predicting outcomes may be improved. ObjectiveWe propose that BSA weighted LVEDD (bLVEDD) is a more accurate predictor of outcomes in patients undergoing CABG compared to simply using LVEDD alone. MethodsThis study was a comprehensive retrospective cohort study that was conducted across multiple medical centers. The inclusion criteria for this study were patients who were admitted for treatment between October 2016 and May 2021. Only elective surgery patients were included in the study, while those undergoing emergency surgery were not considered. All participants in the study received standard care, and their clinical data were collected through the institutional registry in accordance with the guidelines set forth by the Society of Thoracic Surgeons National Adult Cardiac Database. bLVEDD was defined as LVEDD divided by BSA. The primary outcome was in-hospital all-cause mortality (30 days), and the secondary outcomes were postoperative severe adverse events, including use of extracorporeal membrane oxygenation, multiorgan failure, use of intra-aortic balloon pump, postoperative stroke, and postoperative myocardial infarction. ResultsIn total, 9474 patients from 5 centers under the Chinese Cardiac Surgery Registry were eligible for analysis. We found that a high LVEDD was a negative factor for male patients’ mortality (odds ratio 1.44, P
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