| Autor: |
Chien-Chou Hsiao, Jen-Tien Wung, Lon-Yen Tsao, Weng-Cheng Chang |
| Jazyk: |
angličtina |
| Rok vydání: |
2009 |
| Předmět: |
|
| Zdroj: |
Journal of the Formosan Medical Association, Vol 108, Iss 1, Pp 72-77 (2009) |
| Druh dokumentu: |
article |
| ISSN: |
0929-6646 |
| DOI: |
10.1016/S0929-6646(09)60035-8 |
| Popis: |
Optimal time to surgical ligation of patent ductus arteriosus (PDA) in very-low-birth-weight (< 1500 g) premature infants remains an area of controversy. We compared the outcomes of early or late ligation of medical refractory PDA in very-low-birth-weight premature infants. Fifty-six infants underwent surgical closure of PDA after failure of or having contraindications to medical treatment. Thirteen infants were in the early ligation (≤ 14 days) and 43 in the late ligation (> 14 days) groups. Basic clinical features, major morbidity of prematurity and mortality were compared. Clinical features and major outcomes were similar. The early ligation group had earlier onset of symptomatic PDA (5.7 ± 1.6 days vs. 8.1 ± 3.6 days, p = 0.024), and fewer days of total parenteral nutrition (TPN) (39.6 ± 13.9 days vs. 60.4 ± 31.4 days, p = 0.025) and ventilator use (11.1 ± 6.7 days vs. 18.6 ± 10.5 days, p = 0.019). Early ligation of medical refractory PDA in very-low-birth-weight premature infants improves enteral feeding tolerance and reduces TPN and ventilator use, but long-term benefits need further investigation. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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